CUL9 Recombinant Protein, Unconjugated, E. coli

Catalog Number: ASB-OPCD02560
Article Name: CUL9 Recombinant Protein, Unconjugated, E. coli
Biozol Catalog Number: ASB-OPCD02560
Supplier Catalog Number: OPCD02560
Alternative Catalog Number: ASB-OPCD02560-10UG, ASB-OPCD02560-200UG, ASB-OPCD02560-50UG
Manufacturer: Aviva
Host: E. coli
Category: Proteine/Peptide
Application: Control, WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: CUL-9,cullin-9,H7AP1,p53-associated parkin-like cytoplasmic protein,PARC,parkin-like cytoplasmic p53 binding protein,UbcH7-associated protein 1.
Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).
Concentration: 200 ug/mL (prior to lyoph)
Molecular Weight: 55kDa
Tag: N-terminal His and GST Tag
NCBI: 23113
Source: E.coli
Purity: >90%
Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.