24-hydroxycholesterol 7-alpha-hydroxylase,CHAP,cholesterol 7-alpha-hydroxylase,cholesterol 7-alpha-monooxygenase,CYP7,CYP7S1,CYPVII,cytochrome P450 (cholesterol hydroxylase 7 alpha),cytochrome P450 7A1,cytochrome P450, 7a1,cytochrome P450, family 7, subfamily a, polypeptide 1.
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.