GREM1 Recombinant Protein, Unconjugated, E. coli

Product Overview

• Article Name: GREM1 Recombinant Protein, Unconjugated, E. coli
• Biozol Catalog Number: ASB-OPCD03675
• Supplier Catalog Number: OPCD03675
• Alternative Catalog Number: ASB-OPCD03675-10UG, ASB-OPCD03675-200UG, ASB-OPCD03675-50UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Rat
• Conjugation: Unconjugated
• Alternative Names: Cktsf1b1,cysteine knot superfamily 1, BMP antagonist 1,down-regulated in Mos-transformed cells protein,drm,gremlin 1 homolog, cysteine knot superfamily,gremlin-1.

Product Description

Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2, inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (PubMed:15528323). Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.

Product Properties

• Concentration: 200 ug/mL (prior to lyoph)
• Molecular Weight: 22kDa
• Tag: N-terminal His Tag
• NCBI: 50566
• Source: E.coli
• Purity: > 95%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.