MBD2 Recombinant Protein, Unconjugated, E. coli

Product Overview

• Article Name: MBD2 Recombinant Protein, Unconjugated, E. coli
• Biozol Catalog Number: ASB-OPCD05150
• Supplier Catalog Number: OPCD05150
• Alternative Catalog Number: ASB-OPCD05150-10UG, ASB-OPCD05150-200UG, ASB-OPCD05150-50UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: demethylase,DMTase,methyl-CpG-binding domain protein 2,Methyl-CpG-binding protein MBD2,NY-CO-41.

Product Description

Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

Product Properties

• Concentration: 150 ug/mL (prior to lyoph)
• Molecular Weight: 36kDa
• Tag: N-terminal His Tag
• NCBI: 8932
• Source: E.coli
• Purity: > 90%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.