SIGIRR Recombinant Protein, Unconjugated, E. coli

Product Overview

• Article Name: SIGIRR Recombinant Protein, Unconjugated, E. coli
• Biozol Catalog Number: ASB-OPCD06970
• Supplier Catalog Number: OPCD06970
• Alternative Catalog Number: ASB-OPCD06970-10UG, ASB-OPCD06970-200UG, ASB-OPCD06970-50UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Rat
• Conjugation: Unconjugated
• Alternative Names: RGD1306732,single Ig IL-1-related receptor,single Ig IL-1R-related molecule,single immunoglobulin and toll-interleukin 1 receptor (TIR) domain,single immunoglobulin domain-containing IL1R-related protein,TIR8,toll/interleukin-1 receptor 8.

Product Description

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).

Product Properties

• Concentration: 200 ug/mL (prior to lyoph)
• Molecular Weight: 17kDa
• Tag: N-terminal His Tag
• NCBI: 309106
• Source: E.coli
• Purity: > 95%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.