SIRT3 Recombinant Protein, Unconjugated, E. coli

Product Overview

• Article Name: SIRT3 Recombinant Protein, Unconjugated, E. coli
• Biozol Catalog Number: ASB-OPCD07002
• Supplier Catalog Number: OPCD07002
• Alternative Catalog Number: ASB-OPCD07002-10UG, ASB-OPCD07002-200UG, ASB-OPCD07002-50UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase,NAD-dependent deacetylase sirtuin-3, mitochondrial,NAD-dependent protein deacetylase sirtuin-3, mitochondrial,regulatory protein SIR2 homolog 3,silent mating type information regulation 2, S.cerevisiae, homolog 3,SIR2L3,sir2-like 3,SIR2-like protein 3,sirtuin type 3.

Product Description

NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:19535340). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090). Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O (PubMed:16788062, PubMed:18680753, PubMed:24121500, PubMed:24252090, PubMed:19535340). Contributes to the regulation of the cellular energy metabolism (PubMed:24252090). Important for regulating tissue-specific ATP levels (PubMed:18794531). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).

Product Properties

• Concentration: 200 ug/mL (prior to lyoph)
• Molecular Weight: 32kDa
• Tag: N-terminal His Tag
• NCBI: 23410
• Source: E.coli
• Purity: > 90%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.