SIRT3 Recombinant Protein, Unconjugated, E. coli

Product Overview

• Article Name: SIRT3 Recombinant Protein, Unconjugated, E. coli
• Biozol Catalog Number: ASB-OPCD07003
• Supplier Catalog Number: OPCD07003
• Alternative Catalog Number: ASB-OPCD07003-10UG, ASB-OPCD07003-200UG, ASB-OPCD07003-50UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Mouse
• Conjugation: Unconjugated
• Alternative Names: 2310003L23Rik,AI848213,mitochondrial protein lysine deacetylase,mSIR2L3,NAD-dependent deacetylase sirtuin-3,NAD-dependent protein deacetylase sirtuin-3,regulatory protein SIR2 homolog 3,Si,silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3,Sir2l3,SIR2-like protein 3,SIRT3L mitochondrial.

Product Description

NAD-dependent protein deacetylase (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655). Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O (PubMed:16790548, PubMed:18794531, PubMed:21172655). Contributes to the regulation of the cellular energy metabolism (PubMed:23835326). Important for regulating tissue-specific ATP levels (PubMed:18794531, PubMed:24252090). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301).

Product Properties

• Concentration: 200 ug/mL (prior to lyoph)
• Molecular Weight: 29/16kDa
• Tag: N-terminal His Tag
• NCBI: 64384
• Source: E.coli
• Purity: > 90%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.