PTN Recombinant Protein, Unconjugated

Product Overview

• Article Name: PTN Recombinant Protein, Unconjugated
• Biozol Catalog Number: ASB-OPCD08068
• Supplier Catalog Number: OPCD08068
• Alternative Catalog Number: ASB-OPCD08068-10UG, ASB-OPCD08068-200UG, ASB-OPCD08068-50UG
• Manufacturer: Aviva
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: HARP,HBBM,HB-GAM,HBGF8,HBGF-8,HBNF,HBNF-1,heparin affin regulatory protein,heparin-binding brain mitogen,heparin-binding growth factor 8,heparin-binding growth-associated molecule,heparin-binding neurite outgrowth promoting factor,heparin-binding neurite outgrowth-promoting factor 1,NEGF1,OSF-1,osteoblast-specific factor 1,pleiotrophin,pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1).

Product Description

Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).

Product Properties

• Concentration: 200 ug/mL (prior to lyoph)
• Molecular Weight: 17kDa
• Tag: N-terminal His Tag
• NCBI: 5764
• Source: 293-F Cells
• Purity: > 95%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.