UBE2D2 Recombinant Protein (Human), E. coli

Product Overview

• Article Name: UBE2D2 Recombinant Protein (Human), E. coli
• Biozol Catalog Number: ASB-OPED00152
• Supplier Catalog Number: OPED00152
• Alternative Catalog Number: ASB-OPED00152-100UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: (E3-independent) E2 ubiquitin-conjugating enzyme D2,E2 ubiquitin-conjugating enzyme D2,E2(17)KB2,p53-regulated ubiquitin-conjugating enzyme 1,PUBC1,UBC4,UBC4/5,UBCH4,UBCH5B,ubiquitin carrier protein D2,ubiquitin conjugating enzyme E2D 2,ubiquitin-conjugating enzyme E2 D2,Ubiquitin-conjugating enzyme E2(17)KB 2,ubiquitin-conjugating enzyme E2-17 kDa 2,ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5),ubiquitin-protein ligase D2.

Product Description

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-48-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

Product Properties

• Molecular Weight: 18 kDa
• NCBI: 7322
• Purity: >90% (SDS-PAGE)
• Form: Liquid. In TRIS-HCl, pH 7.5, containing 150mM NaCl and 0.5mM DTT.