E2 ubiquitin-conjugating enzyme L6,retinoic acid induced gene B protein,Retinoic acid-induced gene B protein,RIG-B,UBCH8,ubiquitin carrier protein L6,ubiquitin conjugating enzyme E2L 6,ubiquitin/ISG15-conjugating enzyme E2 L6,ubiquitin-protein ligase L6.
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.