HCV NS3 His, Hepatitis C Virus NS3 Recombinant, His Tag
HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the hosts immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Concentration:
1 mg/ml
Molecular Weight:
28 kDa
Tag:
Fused to 36 His Tag at N-terminus
Purity:
Protein is >95% pure as determined by SDS-PAGE
Form:
Liquid 20mM Tris-HCl (pH 8), 1mM DTT & 10% glycerol
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