ITPA Protein

Product Overview

• Article Name: ITPA Protein
• Biozol Catalog Number: ASB-OPPA02321
• Supplier Catalog Number: OPPA02321
• Alternative Catalog Number: ASB-OPPA02321-5UG
• Manufacturer: Aviva
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: DEE35, My049, ITPase, NTPase, C20orf37, dJ794I6.3, HLC14-06-P

Product Description

ITPA enzyme catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP is exercised as a substrate for purine nucleotide pathways. IMP is phosphorylated to ITP, and ITPA mediates the concentration of ITP in the cell by changing ITP back to IMP. Defects in ITPA result in ITPA deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.

Product Properties

• NCBI: 3704
• UniProt: Q9BY32
• Source: E. coli
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Form: ITPA Human solution containing 20mM Tris pH-8, & 10% glycerol. Physical appearance: Sterile filtered colorless solution.