Transforming Growth Factor-beta 1 (TGF-beta 1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-beta 1 signals through SMAD proteins via the TGF-beta1 RI and RII receptors. Mature human TGF-beta1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25.6 kDa.
Molecular Weight:
25.6 kD
Source:
HEK 293 cells
Purity:
95% as determined by: reducing and non-reducing SDS-PAGE
Form:
Sterile filtered white lyophilized (freeze-dried) powder. Lyophilized from a sterile filtered aqueous solution containing 10 mM Glycine, 50 mM NaCl, 10% Trehalose, and BSA (4:1 protein to BSA Ratio), pH 4.0.
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