GABPB2 is the GA-binding protein transcription factor, beta subunit. It forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. GABPB2 may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.