RARA antibody - middle region (P100861_P050), Rabbit, Polyclonal
Biozol Catalog Number:
ASB-P100861_P050
Supplier Catalog Number:
P100861_P050
Alternative Catalog Number:
ASB-P100861_P050-100UL, ASB-P100861_P050-25UL
Manufacturer:
Aviva
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Bovine, Canine, Human, Mouse, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human RARA
Alternative Names:
RAR, NR1B1
Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
