GTF2H2 Antibody - C-terminal region

Catalog Number: ASB-P100894_T100
Article Name: GTF2H2 Antibody - C-terminal region
Biozol Catalog Number: ASB-P100894_T100
Supplier Catalog Number: P100894_T100
Alternative Catalog Number: ASB-P100894_T100-25UL,ASB-P100894_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Canine, Equine, Human, Mouse, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2H2
Alternative Names: p44, BTF2, TFIIH, BTF2P44, T-BTF2P44
GTF2 is encoded by a gene that is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 44kDa
NCBI: 2966
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Lung
WB Suggested Anti-GTF2H2 Antibody Titration: 1 ug/ml
Positive Control: Jurkat cell lysateGTF2H2 is supported by BioGPS gene expression data to be expressed in Jurkat
Host: Rabbit
Target Name: GTF2H2
Sample Tissue: Human 293T
Antibody Dilution: 1.0ug/ml
GTF2H2 antibody - C-terminal region (P100894_T100) in Human 293T using Western Blot