NFKBIA Antibody - N-terminal region

Catalog Number: ASB-P100940_P050
Article Name: NFKBIA Antibody - N-terminal region
Biozol Catalog Number: ASB-P100940_P050
Supplier Catalog Number: P100940_P050
Alternative Catalog Number: ASB-P100940_P050-25UL,ASB-P100940_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Human, Porcine
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIA
Alternative Names: IKBA, MAD-3, NFKBI, EDAID2
NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 36kDa
NCBI: 4792
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-NFKBIA Antibody
Catalog Number: P100940_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-NFKBIA Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung
Rabbit Anti-NFKBIA antibody
Catalog Number: P100940_P050
Paraffin Embedded Tissue: Human Brain cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
NFKBIA antibody - N-terminal region (P100940_P050) in Human Lung using Western Blot