Bone Morphogenetic Protein-4 (BMP-4) is an extracellular multifunctional signaling cytokine that is also a member of the TGF-beta family. BMP-4 can bind with the TGF-beta receptor and trigger SMAD protein signal transduction. BMP-4 has a significant expression in the prostate, it plays a vital role in the development of mesoderm into bones and the development of the epidermis and Dorsal-Ventral axis.
Molecular Weight:
The protein has a calculated MW of 12.88 kDa. The protein migrates as 12 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 20 mM sodium carbonate, pH 9.0. If you have any concerns or special requirements, please confirm with us.
Sequence:
Amino acid sequence derived from Human BMP-4 (Met302-Arg408)(P12644) was expressed with 6*His tag at the C-terminus.
Application Notes:
Human
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