BMP2, BMP2A, Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A
Bone morphogenetic protein-2 (BMP-2) is a kind of bone growth regulator, belonging to protein transforming growth factor-beta(TGF-beta) superfamily. BMP-2 protein is involved in hedgehog pathway, TGF-beta signaling pathway and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMP, which have been proved to be effective in inducing osteoblast differentiation in many cell types. The active form of BMP-2 can be composed of dimers of two identical proteins or heterodimers of two related bone morphogenetic proteins.
