Ciliary Neurotrophic Factor (CNTF) is the member of IL-6 cytokine family and mainly expressed in the nervous system. Mouse CNTF shares 84% sequence homology with human CNTF. CNTF is 22.9 kDa neurotrophic factor containing 110 residues, which shows multiple effects in vertebrate retinogenesis. Besides, CNTF acts as a promoter that not only accelerates adult neurogenesis but also increases the survival of neuron after injury.
Molecular Weight:
The protein has a calculated MW of 23.40 kDa.The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us
Sequence:
Amino acid sequence derived from Mouse CNTF (Ala2-Met198)(P51642) was expressed with 6*His tag at the C-terminus
Application Notes:
Mouse
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