Anti-HMGCR Recombinant Antibody, IgG2a, Clone: [CL0259], Mouse, Monoclonal

Product Overview

• Article Name: Anti-HMGCR Recombinant Antibody, IgG2a, Clone: [CL0259], Mouse, Monoclonal
• Biozol Catalog Number: ATA-AMAB90618R
• Supplier Catalog Number: AMAb90618R
• Alternative Catalog Number: ATA-AMAB90618R-100, ATA-AMAB90618R-25
• Manufacturer: Atlas Antibodies
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human

Product Description

Recombinant Mouse Monoclonal Anti-HMGCR Antibody against Human 3-hydroxy-3-methylglutaryl-coa reductase. Validated for Immunohistochemistry and Western Blot

Product Properties

• Clonality: Monoclonal
• Concentration: 1
• Clone Designation: [CL0259]
• Isotype: IgG2a
• NCBI: 3156
• UniProt: P04035
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Images

Immunohistochemical staining of human breast cancer shows moderate cytoplasmic positivity in tumor cells.

Immunohistochemical staining of human uterine cervix shows moderate cytoplasmic positivity in squamous epithelial cells.

Immunohistochemical staining of human fallopian tube shows moderate to strong cytoplasmic positivity in glandular cells.

Immunohistochemistry analysis in human liver and skeletal muscle tissues using AMAb90618 antibody. Corresponding HMGCR RNA-seq data are presented for the same tissues.

Immunohistochemical staining of human skeletal muscle shows no positivity in myocytes as expected.

Immunohistochemical staining of human liver cancer shows strong cytoplasmic positivity in tumor cells.

Western blot analysis in MCF-7 cells transfected with control siRNA, target specific siRNA probe 1 and 2, using Anti-HMGCR antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.