The heterobifunctional linker DBCO-PEG4-alkyne contains an Alkyne and a DBCO moiety which enable the possibility to perform two sequential click reactions in an orthogonal way. Therefore this linker offers a great potential to cross link azide containing biomolecules by just using high efficient Click Chemistry. The introduction of the hydrophilic PEG4 spacer reduces aggregation and precipitation during the labeling reaction and also minimizes steric hindrance between the conjugate. There is also the possibility to selectively click the alkyne before the DBCO [1]. Therefore this linker offers great potential for the synthesis of Antibody-drug-conjugates (ADC).
Molecular Weight:
518.24 g/mol
Purity:
95% (HPLC)
Form:
Oil
CAS Number:
[2741418-16-4]
Formula:
C30H34N2O6
Application Notes:
click chemistry
DBCO-PEG4-Alkyne
DBCO-PEG4-Alkyne
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