Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the con
The prognosis of gastric adenocarcinoma suggests that TGFbeta1 has great potential. a The pan cancer expression of TGFbeta1 in the TCGA database. b The pan cancer expression of TGFbeta1 in paired samples in the TCGA database. c The expression of TGFbeta1 in the dataset. d The expression of TGFbeta1 in the dataset. e T staging results of TGFbeta1. f The differential expression of TGFbeta1 in the quality of life of different patients. g Comparing the prognosis between high and low TGFbeta1 groups based on the g KM survival curve. h Analyze the predictive accuracy and efficacy of TGFbeta1 in GC queue diagnosis. i Diagnostic prediction of TGFbeta1 in different T stages of GC queue. *p<0.05, **p<0.01, ***p<0.001.Index in PubMed under a CC BY license. PMID: 39991579
The association between TGFbeta1 and the immune microenvironment associated with GC tumors. a TGFbeta1 pan cancer status and tumor associated immune cell correlation heatmap in TCGA database. b The expression of cell markers in the dataset. c GC tumor associated immune cells and TGFbeta1 correlation bar chart. d Box plot of the correlation between TGFbeta1 differential expression group and macrophages. e Scatter plot showing the association between TGFbeta1 and macrophages. f The correlation results between TGFbeta1 and GC immune infiltrating cells in TIMER database. g Correlation heatmap between TGFbeta1 and macrophage subtypes. *p<0.05, **p<0.01, ***p<0.001.Index in PubMed under a CC BY license. PMID: 39991579
There is a close correlation between TGFbeta1 and polarization of M2c macrophages. a The expression results of different biomarkers in the dataset. b The expression results of different biomarkers in the dataset. c The expression results of different biomarkers in the dataset. d Heat map of the association between TGFbeta1 and different subtypes of macrophages. e The relationship between TGFbeta1 and different subtypes of macrophage marker networks. *p<0.05, **p<0.01, ***p<0.001.Index in PubMed under a CC BY license. PMID: 39991579
Different inducers promote polarization of different subtypes of macrophages. a The CCK-8 method was used to detect the survival of M0 macrophages after 24 h of IL-4 intervention. b The CCK-8 method was used to detect the survival of M0 macrophages after 24 h of intervention with TGFbeta1. c The CCK-8 method was used to detect the survival of M0 macrophages after LPS intervention for 24 h. d RT-qPCR was used to detect the expression of CD86 mRNA. e RT-qPCR was used to detect the expression of iNOS mRNA. f RT-qPCR was used to detect the expression of CD206 mRNA. g RT-qPCR was used to detect the expression of IL1R2 mRNA. h RT-qPCR was used to detect the expression of CD163 mRNA. i RT-qPCR was used to detect the expression of TGFbeta mRNA. j ELISA detects TNF - alpha levels. k ELISA was used to detect IL-10 levels. l ELISA detects the content of TGFbeta1. m The WB results of different interventions on histone expression. f TNF-alpha protein expression results. f IL-10 protein expression results. f TGFbeta1 protein expression results. *p<0.05, **p<0.01, ***p<0.001.Index in PubMed under a CC BY license. PMID: 39991579
The effect of M2 subtype macrophages on TGFbeta1 related pathway and epithelial mesenchymal transition in gastric cancer cells. a Cell intervention pattern diagram. b RT-qPCR was used to detect the levels of TGFbeta mRNA in different intervention groups. c ELISA was used to test the expression of TNF-alpha in different intervention groups. d ELISA test the expression of IL-10 in different intervention groups. e ELISA was used to test the expression of TGFbeta1 in different intervention grou
Western blot analysis of TGF beta 1 expression in A549 lysate.
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature.
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