A synthesized peptide derived from human TDT Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5-triphosphate to the 3-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
Alternative Names:
DNA nucleotidylexotransferase, DNTT, TDT, Terminal addition enzyme, Terminal transferase
Boster Bio Anti-TDT DNTT Monoclonal Antibody catalog M05546. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.