Human recombinant OGG1 (8-oxoguanine DNA glycosylase) protein, AF
Biozol Catalog Number:
BOB-PROTO15527-2-20UG
Supplier Catalog Number:
PROTO15527-2-20ug
Alternative Catalog Number:
BOB-PROTO15527-2-20UG-20UG
Manufacturer:
Boster Bio
Category:
Proteine/Peptide
Application:
Cell Culture
Species Reactivity:
Human
Alternative Names:
HMMH, MUTM, OGH1, HOGG1
8-oxoguanine DNA glycosylase-1 (OGG1) is a major DNA glycosylase that plays a critical role in n base-excision repair (BER) of oxidative DNA damage to nuclear and mitochondrial DNA (mtDNA) to remove 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-OH-dG). OGG1 is a 38.8 kDa protein containing 52 amino acid it found in bacterial, archaeal and eukaryotic species. OGG1 in DNA causes G:C to T:A transversions and, therefore, it could be responsible for mutations that lead to carcinogenesis.
Molecular Weight:
The protein has a calculated MW of 39.61 kDa. The protein migrates as 40 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
