Human recombinant GFAP protein, AF

Catalog Number: BOB-PROTP14136-5UG
Article Name: Human recombinant GFAP protein, AF
Biozol Catalog Number: BOB-PROTP14136-5UG
Supplier Catalog Number: PROTP14136-5ug
Alternative Catalog Number: BOB-PROTP14136-5UG-5UG
Manufacturer: Boster Bio
Category: Proteine/Peptide
Application: Cell Culture
Species Reactivity: Human
Alternative Names: Glial fibrillary acidic protein
GFAP (Glial Fibrillary Acidic Protein) is a protein primarily found in CNS astrocytes. Increased GFAP immunoreactivity indicates gliosis, a response to neural damage. GFAP defects cause Alexander disease, a rare CNS disorder with astrocytic Rosenthal fiber accumulation. The infantile form leads to myelination failure and early mortality, while the juvenile or adult forms present with ataxia, bulbar signs, spasticity, progressing more gradually.
Molecular Weight: The protein has a calculated MW of 51 kDa. The protein migrates as 50-55 kDa under reducing condition (SDS-PAGE analysis).
Tag: His Tag (C-term)
UniProt: P14136
Source: Escherichia coli
Form: The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Sequence: A DNA sequence encoding Human GFAP Protein (P14136)(Met1-Met432) was expressed with polyhistidine tag at the C-terminus.