Mouse recombinant BMP-4 (Bone morphogenetic protein-4) protein, AF
Biozol Catalog Number:
BOB-PROTP21275-1-5UG
Supplier Catalog Number:
PROTP21275-1-5ug
Alternative Catalog Number:
BOB-PROTP21275-1-5UG-5UG
Manufacturer:
Boster Bio
Category:
Proteine/Peptide
Application:
Cell Culture
Species Reactivity:
Mouse
Alternative Names:
BMP-2B, DVR4
Bone Morphogenetic Protein-4 (BMP-4) predicts a molecular mass of 13 kDa, is a vital regulatory molecule that functions throughout human development in mesoderm induction, tooth development, limb formation, bone induction, and fracture repair and is overexpressed in patients who have fibrodysplasia ossificans progressiva. BMP-4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures.
Molecular Weight:
The protein has a calculated MW of 12.88 kDa. The protein migrates as 11-17 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 20 mM sodium carbonate, pH 4.5. If you have any concerns or special requirements, please confirm with us.
Sequence:
MKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCRwith polyhistidine tag at the C-terminus.
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