TYRP1 (Tyrosinase Related Protein 1)(TA99), 0.2mg/mL, Clone: [TA99], Mouse, Monoclonal
Biozol Catalog Number:
BOT-BNUB0806-500
Supplier Catalog Number:
BNUB0806-500
Alternative Catalog Number:
BOT-BNUB0806-500-500UL
Manufacturer:
Biotium
Host:
Mouse
Category:
Antikörper
Application:
FC, IF, IHC, IP
Species Reactivity:
Human, Mouse
Immunogen:
SK-MEL-23 cells
Alternative Names:
5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP
This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL|Immunohistology (frozen only) 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
* VAT and and shipping costs not included. Errors and price changes excepted
