Beta-2-Microglobulin (B2M)(246-E9.E7), 0.2mg/mL, Clone: [246-E9.E7|same as HLA.ABC.m2], Mouse, Monoclonal

Product Overview

• Article Name: Beta-2-Microglobulin (B2M)(246-E9.E7), 0.2mg/mL, Clone: [246-E9.E7|same as HLA.ABC.m2], Mouse, Monoclonal
• Biozol Catalog Number: BOT-BNUB1039-500
• Supplier Catalog Number: BNUB1039-500
• Alternative Catalog Number: BOT-BNUB1039-500-500UL
• Manufacturer: Biotium
• Host: Mouse
• Category: Antikörper
• Application: FC, Functional Studies, IF, IP
• Species Reactivity: Human
• Immunogen: Human PBLs from a T-cell acute lymphoblastic leukemia (T-ALL) patient
• Alternative Names: B2M, Beta 2 microglobulin

Product Description

Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human Beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection. Clone 246 E9.E7 is the same as HLA.ABC.m2.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Properties

• Clonality: Monoclonal
• Concentration: 0.2 mg/mL
• Clone Designation: [246-E9.E7|same as HLA.ABC.m2]
• Molecular Weight: 12 kDa
• UniProt: P61769
• Buffer: PBS, 0.05% BSA, 0.05% azide
• Source: Animal

Application Notes

• Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Does not react with non-human primates, others not known|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user