FABP5 (Marker of Metastatic Potential in Colorectal Cancer)(FABP5/3750), 0.2mg/mL, Clone: [FABP5/3750], Mouse, Monoclonal
Biozol Catalog Number:
BOT-BNUB3750-500
Supplier Catalog Number:
BNUB3750-500
Alternative Catalog Number:
BOT-BNUB3750-500-500UL
Manufacturer:
Biotium
Host:
Mouse
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human
Immunogen:
Recombinant full-length human FABP5 protein
Alternative Names:
FABP5, E-FABP, EFABP, PA-FABP, PAFABP
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
