IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(rIM260), 0.2mg/mL, Clone: [rIM260], Mouse, Monoclonal
Biozol Catalog Number:
BOT-BNUB3775-500
Supplier Catalog Number:
BNUB3775-500
Alternative Catalog Number:
BOT-BNUB3775-500-500UL
Manufacturer:
Biotium
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Recombinant full-length human IGHM protein
Alternative Names:
AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region
Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.