MHC I(246-B8.E7), 1mg/mL, Clone: [246-B8.E7], Mouse, Monoclonal

Catalog Number: BOT-BNUM1054-50
Article Name: MHC I(246-B8.E7), 1mg/mL, Clone: [246-B8.E7], Mouse, Monoclonal
Biozol Catalog Number: BOT-BNUM1054-50
Supplier Catalog Number: BNUM1054-50
Alternative Catalog Number: BOT-BNUM1054-50-50UL
Manufacturer: Biotium
Host: Mouse
Category: Antikörper
Application: IF
Species Reactivity: Human, Mouse, Primate
Immunogen: Human peripheral blood leukocytes
Alternative Names: HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A B C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Clonality: Monoclonal
Concentration: 1 mg/mL
Clone Designation: [246-B8.E7]
Molecular Weight: ~41 kDa
UniProt: P01889
Buffer: PBS, no BSA, no azide
Source: Animal
Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user