CD95/FAS Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit

Product Overview

• Article Name: CD95/FAS Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit
• Biozol Catalog Number: BSS-BS-0215R-PE-CY7
• Supplier Catalog Number: bs-0215R-PE-Cy7
• Alternative Catalog Number: BSS-BS-0215R-PE-CY7-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: PE/Cy7
• Alternative Names: lpr, APO1, APT1, CD95, TNFR6, Tnfrsf6, AI196731, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, Fas

Product Description

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 14102
• UniProt: P25446
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from mouse FAS
• Target: CD95/FAS

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100)