Histone H3 Polyclonal Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit

Product Overview

• Article Name: Histone H3 Polyclonal Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit
• Biozol Catalog Number: BSS-BS-0349R-BF594
• Supplier Catalog Number: bs-0349R-BF594
• Alternative Catalog Number: BSS-BS-0349R-BF594-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: BF594
• Alternative Names: Histone H3, H3.1, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FA, H3FL, H3FC, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, H3.2, HIST2H3A, HIST2H3C, HIST2H3D, H3F2, H3FM, H3.3, H3F3A, H3F3B, H3.3A, H3.3B, H3F3, PP781, H3.3C, H3F3C, H3.5, H3.1t, HIST3H3, H3FT

Product Description

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 3020
• UniProt: P84243
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human Histone H3
• Target: Histone H3

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)