PIWIL1 Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit

Catalog Number: BSS-BS-0665R-BF350
Article Name: PIWIL1 Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit
Biozol Catalog Number: BSS-BS-0665R-BF350
Supplier Catalog Number: bs-0665R-BF350
Alternative Catalog Number: BSS-BS-0665R-BF350-100
Manufacturer: Bioss
Host: Rabbit
Category: Antikörper
Application: IF, WB
Species Reactivity: Human
Conjugation: BF350
Alternative Names: PIWI, Piwi-like protein 1, PIWIL1
Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).
Clonality: Polyclonal
Concentration: 1ug/ul
NCBI: 416804
UniProt: A6N7Y9
Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: KLH conjugated synthetic peptide derived from chicken PIWIL1
Target: PIWIL1
Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)