OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB
Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).