phospho-Cofilin (Ser24) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: phospho-Cofilin (Ser24) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-10252R-BIOTIN
• Supplier Catalog Number: bs-10252R-Biotin
• Alternative Catalog Number: BSS-BS-10252R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P
• Species Reactivity: Rat
• Conjugation: Biotin
• Alternative Names: Cofilin/CFL1 Ser24, 18 kDa phosphoprotein, CFL 1, CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, p18, COF1_HUMAN.

Product Description

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 1072
• UniProt: p23528
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human CFL1/CFL2 around the phosphorylation site of Ser24
• Target: phospho-Cofilin (Ser24)

Application Notes

• Application Dilute: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)