Dishevelled 2 homologous to Drosophila dsh, Dishevelled dsh homolog 2, Dishevelled-2, Dishevelled2, DSH homolog 2, DVL 2, Dvl2, DVL2_HUMAN, Segment polarity protein dishevelled homolog DVL 2, Segment polarity protein dishevelled homolog DVL-2, Segment polarity protein dishevelled homolog DVL2.
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008].