Endoplasmic reticulum resident protein 44, Endoplasmic reticulum resident protein 44 kDa, Endoplasmic reticulum resident protein ERp44, ER protein 44, ERP44, KIAA0573, PDIA10, Protein disulfide isomerase family A, member 10, Thioredoxin domain containing 4 (endoplasmic reticulum), Thioredoxin domain containing protein 4, UNQ532/PRO1075, ERP44, ERP44_HUMAN.
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
