phospho-MCM2 (Ser53) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: phospho-MCM2 (Ser53) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-10608R-BIOTIN
• Supplier Catalog Number: bs-10608R-Biotin
• Alternative Catalog Number: BSS-BS-10608R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: MCM4 (phospho S53), MCM2(phospho-Ser53), MCM2(phospho Ser53), MCM2 (phospho S54), p-MCM2(Ser53), p-MCM2(S53), rat MCM4 (phospho S54), BM28, CCNL 1, CCNL1, CDC like 1, CDC like-1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, cyclin like-1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae), MCM2 minichromosome maintenance deficient 2, mitotin, MCM2_HUMAN, MCM2_MOUSE, MGC10606, Minichromosome maintenance complex component 2, Minichromosome maintenance deficient 2 (mitotin), Minichromosome maintenance deficient 2 mitotin, Minichromosome maintenance protein 2, Minichromosome maintenance protein 2 homolog, Mitotin, Nuclear protein BM28, OTTHUMP00000216047, OTTHUMP00000216050.

Product Description

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 4171
• UniProt: P49736
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated Synthesised phosphopeptide derived from human MCM2 around the phosphorylation site of Ser53
• Target: phospho-MCM2 (Ser53)

Application Notes

• Application Dilute: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)