Secretogranin V Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: Secretogranin V Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-10762R-BIOTIN
• Supplier Catalog Number: bs-10762R-Biotin
• Alternative Catalog Number: BSS-BS-10762R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Mouse, Rat
• Conjugation: Biotin
• Alternative Names: 7B2, SgV, P7B2, SGNE1, Neuroendocrine protein 7B2, Pituitary polypeptide, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I, SCG5

Product Description

Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 6447
• UniProt: P05408
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human Secretogranin-5
• Target: Secretogranin V

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)