Parathyroid Hormone Related Protein, Parathyroid Hormone-related Protein, HHM, MGC14611, Osteostatin, Parathyroid hormon like hormone isoform 2 preproprotein, Parathyroid hormone like hormone, Parathyroid hormone like hormone isoform 1 preproprotein, Parathyroid hormone like protein, Parathyroid hormone like related protein, Parathyroid Hormone Receptor 1, Parathyroid like protein, PLP, PTH related protein, PTH rP, PTHrP, PTHR, PTHRP.
Parathyroid related protein (PTHLH), is a polypeptide hormone produced by almost every tissue of the body and is closely related to parathyroid hormone (PTH). It signals through its receptor, PTHR1, regulating endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. The receptor for this hormone (PTHRP) is responsible for most cases of humoral hypercalcemia of malignancy.