Signal Peptide Peptidase Polyclonal Antibody, HRP Conjugated, Rabbit

Product Overview

• Article Name: Signal Peptide Peptidase Polyclonal Antibody, HRP Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-11178R-HRP
• Supplier Catalog Number: bs-11178R-HRP
• Alternative Catalog Number: BSS-BS-11178R-HRP-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Conjugation: HRP
• Alternative Names: Histocompatibility minor 13, HM 13, HM13, HM13_HUMAN, IMP 1, IMP-1, IMP1, IMPAS, IMPAS-1, Intramembrane Protease 1, Intramembrane protease, Minor Histocompatibility 13, Minor histocompatibility antigen 13, Minor histocompatibility antigen H13, MSTP086, Presenilin like protein 3, Presenilin-like protein 3, PSENL 3, PSENL3, PSL 3, PSL3, Signal peptide peptidase, Signal peptide peptidase beta, SPP, dJ324O17.1, H13, hIMP1, hIMP1 protein.

Product Description

The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 207
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human Signal Peptide Peptidase
• Target: Signal Peptide Peptidase

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)