CASK Polyclonal Antibody, AbBy Fluor-647 Conjugated, BF647, Rabbit

Product Overview

• Article Name: CASK Polyclonal Antibody, AbBy Fluor-647 Conjugated, BF647, Rabbit
• Biozol Catalog Number: BSS-BS-11338R-BF647
• Supplier Catalog Number: bs-11338R-BF647
• Alternative Catalog Number: BSS-BS-11338R-BF647-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF
• Species Reactivity: Rat
• Conjugation: BF647
• Alternative Names: CAGH39, Caki, Calcium/calmodulin dependent serine protein kinase, Calcium/calmodulin dependent serine protein kinase MAGUK family, Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase, Calcium/calmodulin-dependent serine protein kinase, CAMGUK, CAMGUK protein, CAMGUK, drosophila, homolog of antibody casK, CMG, CSKP_HUMAN, DXPri1, DXRib1, FGS4, hCASK, LIN 2, Lin 2 homolog, LIN2 antibody Lin2 homolog, MICPCH, MRXSNA, Pals3, Peripheral plasma membrane protein CASK, Protein lin-2 homolog, TNRC8, Trinucleotide repeat containing 8, Vertebtate LIN2 homolog.

Product Description

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human CASK
• Purity: Purified by Protein A.
• Target: CASK

Application Notes

• Application Dilute: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)