ITM2C Polyclonal Antibody, RBITC Conjugated, Rabbit

Product Overview

• Article Name: ITM2C Polyclonal Antibody, RBITC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-11859R-RBITC
• Supplier Catalog Number: bs-11859R-RBITC
• Alternative Catalog Number: BSS-BS-11859R-RBITC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Conjugation: RBITC
• Alternative Names: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.

Product Description

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 81618
• UniProt: Q9NQX7
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human ITM2C
• Target: ITM2C

Application Notes

• Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)