Pecanex Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-11932R-PE
Supplier Catalog Number:
bs-11932R-PE
Alternative Catalog Number:
BSS-BS-11932R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF
Conjugation:
PE
Alternative Names:
PCNXL1, Pecanex homolog, Pecanex like protein 1, PCX1_HUMAN.
Human Pecanex proteins are homologs of the Drosophila Pecanex protein, a maternal-effect neurogenic protein that is involved in normal development of the fly nervous system. Three human Pecanex homologs exist, designated Pecanex, Pecanex 2, also known as PCNXL2 (pecanex-like 2), and Pecanex 3. Pecanex 2 is a 2,137 amino acid multi-pass membrane protein that exists as five alternatively spliced isoforms characterized by high mutational frequencies and biallelic mutations in colorectal tumors, thereby likely functioning as a target gene in these tumors. Pecanex 2 is encoded by a gene that maps to human chromosome 1q42.2, which is linked to an inherited microduplication. This microduplication that includes Pecanex 2 may play a role in autism and mild mental retardation.
