phospho-GARB1 (Ser434) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: phospho-GARB1 (Ser434) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-12064R-BIOTIN
• Supplier Catalog Number: bs-12064R-Biotin
• Alternative Catalog Number: BSS-BS-12064R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Mouse
• Conjugation: Biotin
• Alternative Names: GABA A Receptor beta 1 phospho S434, GARB1 Ser 434, GABAA receptor subunit beta-1, GABA-A receptor, beta-1 polypeptide, Gabrb-1, Gamma Aminobutyric Acid A Receptor Beta 1, Gamma Aminobutyric Acid Receptor , beta-1, Gamma-aminobutyric acid GABA A receptor, subunit beta 1, Gamma-aminobutyric acid receptor subunit beta-1, GARB1, GABRA1, AW061132, B230208N19Rik, GABAA receptor beta 1, GABAA receptor subunit beta-1, GABA-A receptor, beta-1 polypeptide, Gabrb-1, GABRB1, Gamma aminobutyric acid GABA A receptor beta 1, Gamma Aminobutyric Acid A Receptor Beta 1, Gamma Aminobutyric Acid Receptor , beta-1, Gamma-aminobutyric acid GABA A receptor, subunit beta 1, Gamma-aminobutyric acid receptor subunit beta-1, GARB1, GBRB1_HUMAN.

Product Description

GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R1-3, GABAA Rsigma, GABAA R gamma, GABAA R delta 1 and GABAA R delta 2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human GARB1 around the phosphorylation site of Ser434
• Target: phospho-GARB1 (Ser434)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)