PFKFB3/PFK2 Polyclonal Antibody, FITC Conjugated, Rabbit
Catalog Number:
BSS-BS-12631R-FITC
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| Article Name: | PFKFB3/PFK2 Polyclonal Antibody, FITC Conjugated, Rabbit |
| Biozol Catalog Number: | BSS-BS-12631R-FITC |
| Supplier Catalog Number: | bs-12631R-FITC |
| Alternative Catalog Number: | BSS-BS-12631R-FITC-100 |
| Manufacturer: | Bioss |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IF |
| Species Reactivity: | Mouse, Rat |
| Conjugation: | FITC |
| Alternative Names: | 6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase, 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3, 6-bisphosphatase, 6-P2ase 3, 6-P2ASE brain/placenta-type isozyme, 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme, 6PF 2-K/Fru 2,6 P2ase 3, 6PF-2-K/Fru-2, F263_HUMAN, fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase, Fructose-2, Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase, iPFK 2, iPFK-2, IPFK2, PFK/FBPase 3, PFK2, PFKFB3, Renal carcinoma antigen NY REN 56, Renal carcinoma antigen NY-REN-56, uPFK 2. |
| The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016] |
| Application Dilute: | IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |
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