GALE Polyclonal Antibody, Biotin Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-13265R-BIOTIN
Supplier Catalog Number:
bs-13265R-Biotin
Alternative Catalog Number:
BSS-BS-13265R-BIOTIN-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IHC-Fr, IHC-P, WB
Species Reactivity:
Mouse
Conjugation:
Biotin
Alternative Names:
FLJ95174, FLJ97302, Galactose 4 epimerase UDP, Galactowaldenase, galE, GALE_HUMAN, OTTHUMP00000002991, OTTHUMP00000002994, OTTHUMP00000037931, OTTHUMP00000044857, SDR1E1, short chain dehydrogenase/reductase family 1E member 1, UDP galactose 4 epimerase, UDP glucose 4 epimerase, UDP-galactose 4-epimerase, UDP-glucose 4-epimerase.
GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
