GM2A Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: GM2A Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-13452R-BIOTIN
• Supplier Catalog Number: bs-13452R-Biotin
• Alternative Catalog Number: BSS-BS-13452R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Human, Rat
• Conjugation: Biotin
• Alternative Names: SAP-3, GM2-AP, Ganglioside GM2 activator, Cerebroside sulfate activator protein, Sphingolipid activator protein 3, GM2A

Product Description

The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2760
• UniProt: P17900
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human GM2A/SAP3
• Target: GM2A

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)